Therapeutic areas and Protocols
Cardiology
Active Studies - Cardiology
BaxHTN
A randomized, double-blind, placebo-controlled, parallel group study to evaluate the efficacy and safety of Baxdrostat in participants with uncontrolled hypertension taking two or more medications, including participants with resistant hypertension.
LIBREXIA ACS
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Event-Based Study to Demonstrate the Efficacy and Safety of an Oral Factor XIa Inhibitor, Following Recent Acute Coronary Syndrome (ACS)
HERMES
Effects of ziltivekimab versus placebo on morbidity and mortality in patients with chronic heart failure with preserved ejection fraction and systemic inflammation.
LIBREXIA AFL
A Phase 3, randomized, double-blind, double-dummy, parallel-group, active study to evaluate the efficacy and safety of Milvexian, an oral factor XIa Inhibitor, versus apixaban in participants with atrial fibrillation.
Completed Studies - Cardiology
AMETHYST
AMETHYST - D5496C00005
"A Phase 2, multicenter, double-blind, 3-arm, placebo- and active-controlled study to evaluate the efficacy and safety of Verinurad combined with allopurinol in heart failure with preserved ejection fraction."
NODE-303
Multicenter, multinational, open-label study to evaluate the safety of etripamil nasal spray in patients with paroxysmal supraventricular tachycardia. Phase III
AUGUSTUS
CV185316 Open-label, 2x2 factorial, randomized, controlled clinical trial to evaluate the safety of Apixaban compared to a vitamin K antagonist and aspirin compared to aspirin placebo in patients with atrial fibrillation and acute coronary syndrome or percutaneous coronary intervention.
MARINER
RIVAROXDVT3002; Phase 3 BAY 59-7939/17261
Evaluation, in patients with medical conditions, of rivaroxaban versus placebo in reducing the risk of venous thromboembolism after hospital discharge
(MARINER)
DAPA HF
DAPA HF – D1699C00001 Study to evaluate the effect of Dapagliflozin on the incidence of worsening heart failure or cardiovascular mortality in patients with chronic heart failure with reduced ejection fraction
VOYAGER PAD
BAY 59-7939/17454 Phase III, randomized, placebo-controlled, double-blind, international, multicenter study investigating the efficacy and safety of rivaroxaban in reducing the risk of major thrombotic vascular events in patients with symptomatic peripheral arterial disease undergoing lower extremity revascularization procedures.
Cardiovascular
Active Studies - Cardiovascular
BalanceD-HF
"Estudio de fase III, aleatorizado, doble ciego para evaluar el efecto de balcinrenona/dapagliflozina, en comparación con dapagliflozina, sobre el riesgo de episodios de insuficiencia cardíaca y muerte cardiovascular en pacientes con insuficiencia cardíaca y deterioro de la función renal (BalanceD-HF)"
ACCLAIM-Lp(a)
J3L-MC-EZEF
“Un estudio de Fase 3, randomizado, doble ciego, controlado con placebo para investigar el efecto de Lepodisirán en la reducción de eventos adversos cardiovasculares mayores en adultos con lipoproteína(a) elevada, que presentan enfermedad cardiovascular aterosclerótica establecida o corren el riesgo de presentar el primer evento cardiovascular - ACCLAIM-Lp(a)”
Completed Studies - Cardiovascular
SYNCHRONIZE
A Phase III, Randomized, Double-Blind, Parallel-Group, Event-Driven, Cardiovascular Safety Study With BI 456906 Administered Subcutaneously Compared to Placebo in Participants With Overweight or Obesity
SURMOUNT – Obesity
A Phase 3, randomized, double-blind, placebo-controlled study to investigate the effect of Tirzepatide in reducing morbidity and mortality in adults with obesity. This study will investigate the effect of tirzepatide on reducing morbidity and mortality in adults living with obesity and will provide additional evidence of the potential clinical benefits of tirzepatide in this population.
ZEUS
Research study to see how ziltivekimab works compared to placebo in people with cardiovascular disease, chronic kidney disease, and inflammation.
ESPERION
1002-043 - Esperion
"Randomized, double-blind, placebo-controlled study to evaluate the effects of bempedoic acid (ETC-1002) on the occurrence of major cardiovascular events in patients with cardiovascular disease or at high risk of developing it, who do not tolerate statins"
Dermatology
Active Studies - Dermatology
1368-0098
Randomized, double-blind, placebo-controlled, phase IIb/phase III study to evaluate the efficacy and safety of spesolimab in patients with moderate to severe hidradenitis suppurativa
Completed Studies - Dermatology
PSO3001
Phase 3, multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of JNJ-77242113 in the treatment of participants with moderate to severe plaque psoriasis, with randomized withdrawal and retreatment
INCB 18424-319
Phase III, double-blind, randomized, vehicle-controlled study to evaluate the efficacy and safety of ruxolitinib cream in participants with prurigo nodularis; Topical evaluation of ruxolitinib in nodular prurigo (TRuE-PN1)
Diabetes
Active Studies - Diabetes
There are no active studies at this time
Completed Studies - Diabetes
ACHIEVE-3
J2A-MC-GZGU A Phase 3, Randomized, Open-Label Study to Investigate the Efficacy and Safety of Oral LY3502970 Once Daily Compared to Oral Semaglutide in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin (ACHIEVE-3)
MK 0431-845
MK0431-845
Phase III, multicenter, randomized, double-blind, placebo-controlled clinical study to study the efficacy and safety of continued administration of sitagliptin compared to withdrawal of sitagliptin during initiation and titration of insulin glargine (LANTUS®) in participants with type 2 diabetes mellitus
MK 8835-001
MK 8835-001
“Phase III, multicenter, randomized, double-blind, placebo-controlled clinical trial to evaluate the efficacy and safety of ertugliflozin (MK-8835/PF-04971729) in subjects with type 2 diabetes mellitus with stage 3 chronic kidney disease, “whose glycemic control is inadequate with basic antihyperglycemic treatment”
DIA 4003
Protocol 28431754DIA4003
“Randomized, multicenter, double-blind, parallel, placebo-controlled study of the effects of canagliflozin on renal endpoints in adult subjects with type 2 diabetes mellitus.”
HARMONY
LPG 116174
“Long-term, randomized, double-blind, placebo-controlled study to determine the effect of albiglutide added to standard blood glucose-lowering therapies on major cardiovascular events in patients with Type 2 diabetes mellitus.”
VERTIS
MK-8835-004-01/ B1521021
“Randomized, double-blind, placebo-controlled, parallel-group study to evaluate cardiovascular outcomes after treatment with ertugliflozin (MK-8835/PF-04971729) in subjects with type 2 diabetes mellitus and established vascular disease,” the cv study "Vertis."
ABBVIE
Estudio aleatorizado, multipaís, multicéntrico, a doble ciego, paralelo y controlado con placebo sobre los efectos de atrasentan en resultados renales de sujetos con diabetes tipo 2 y nefropatía. SONAR: estudio de nefropatía diabética con atrasentan
SCORED
EFC14875 – SCORED - Multicenter, randomized, double-blind, placebo-controlled, parallel-group study to demonstrate the effects of sotagliflozin on cardiovascular and renal events in patients with type 2 diabetes, cardiovascular risk factors and moderate renal failure
Gastroenterology
Estudios Activos - Gastroenterología
LIBERTY
A Phase 2, multicenter, randomized, double-blind, placebo-controlled, parallel-group study to evaluate the efficacy and safety of dupilumab therapy in patients with moderately to severely active ulcerative colitis with an eosinophilic phenotype.A Study to Investigate the Efficacy and Safety of Dupilumab Therapy Compared to Placebo in Participants >=18 Years of Age With Moderately to Severely Active Ulcerative Colitis with an Eosinophilic Phenotype
AMG 592 20210210
A Phase 2 Long-Term Extension (LTE) Study to Evaluate the Safety and Efficacy of Efavaleukin Alfa in Subjects With Moderately to Severely Active Ulcerative Colitis
DUET-UC
Parexel Number:263114 / Site Number: UC #10002Randomized, double-blind, active-controlled, parallel-group, multicenter Phase 2b study to evaluate the efficacy and safety of combined induction and maintenance therapy with guselkumab and golimumab in participants with moderately to severely active ulcerative colitis.
ASTRO
Phase 3, randomized, double-blind, placebo-controlled, parallel-group, multicenter study to evaluate the efficacy and safety of subcutaneous induction treatment with Guselkumab in participants with moderately to severely active ulcerative colitis.
AMG592 20170104
A Phase 2, dose-finding, randomized, double-blind, placebo-controlled, multicenter study. To evaluate the safety and efficacy of Efavaleukin alfa in induction therapy in participants with moderately to severely active ulcerative colitis
Completed Studies - Gastroenterology
CC-93538-EE-02
“Estudio de extensión de fase 3, multicéntrico, multinacional, abierto, para evaluar la seguridad a largo plazo de CC-93538 en sujetos adultos y adolescentes con esofagitis eosinifílica”
QUASAR
Ulcerative colitis
RLM-MD-04
RLM-MD-04
“52-week, randomized, double-blind, placebo-controlled, phase 3 study to evaluate the safety and efficacy of relamorelin in patients with diabetic gastroparesis”
RLM-MD-03
RLM-MD-03
“46-week, double-blind, placebo-controlled, phase 3 study, with a 6-week randomized drug withdrawal period, to evaluate the safety and efficacy of relamorelin in patients with diabetic gastroparesis”
RLM-MD-02
RLM-MD-02
“12-week, randomized, double-blind, placebo-controlled, phase 3 study to evaluate the safety and efficacy of relamorelin in patients with diabetic gastroparesis”
Gynecology
Active Studies - Gynecology
There are no active studies at this time
Completed Studies - Gynecology
ESTETRA
MIT-Do001-C301: Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial to Evaluate the Efficacy and Safety of Estetrol for the Treatment of Moderate to Severe Vasomotor Symptoms in Postmenopausal Women (E4Comfort I Study)
Hepatology
Active Studies - Hepatology
K-001-201
"Estudio de fase 2, multicéntrico, controlado con placebo, aleatorizado, doble ciego, de 48 semanas para evaluar la eficacia y seguridad de la terapia combinada de K-877-ER y CSG452 en pacientes con esteatohepatitis no alcohólica no cirrótica (NASH) con fibrosis hepática"
Completed Studies - Hepatology
FORTUNA
Phase IIb/III, randomized, double-blind, placebo-controlled study to evaluate the safety and efficacy of cotadutide in participants with non-cirrhotic non-alcoholic steatohepatitis with fibrosis.
Infectology
Active Studies - Infectology
ENANTA
Phase 2b, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of EDP-938 in non-hospitalized adults with acute Respiratory Syncytial Virus infection and at high risk of complications.
Completed Studies - Infectology
VOLITION
A study to evaluate the efficacy, safety, participant choice, and preference of a once-daily oral regimen or a bimonthly long-acting injectable regimen for the treatment of HIV-1 in adults not previously taking antiretroviral therapy.
SUNRISE-3
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Bemnifosbuvir in High-Risk Outpatients with COVID-19.
SCORPIO-HR
A Phase 3, Multicenter, Randomized, Double-Blind, 24-Week Study of the Clinical and Antiviral Effect of S-217622 Compared to Placebo in Non-Hospitalized Participants With COVID-19
BANNER
Estudio abierto, de fase 2a, multicéntrico, aleatorizado, de dos partes, con diseño adaptativo, para evaluar el efecto antiviral, la seguridad y la tolerabilidad de GSK3810109A, un anticuerpo monoclonal humano ampliamente neutralizante específico del VIH-1 en adultos infectados por el VIH-1 sin tratamiento previo con antirretrovirales.
TACKLE
"Estudio fase III, multicéntrico, aleatorizado, doble ciego, controlado con placebo, para determinar la seguridad y eficacia de AZD7442 para el tratamiento de COVID-19 en adultos no hospitalizados"
Lipids
Active Studies - Lipids
There are no active studies at this time
Completed Studies - Lipids
PROMINENT
“PROMINENT Pemafibrate to reduce cardiovascular outcomes by reducing triglycerides in patients with diabetes”
Nephrology
Active Studies - Nephrology
BGB-3111-309
BGB-3111-309: un estudio de fase 3, multicéntrico, aleatorizado, con control activo y abierto para Evaluar la eficacia y seguridad de zanubrutinib en pacientes con membrana primaria Nefropatía. Protocolo de estudio, Versión de enero de 2022.
TRANSCEND-T2D-3
16 pacientes en 4 meses
22 pacientes en 6 meses
Un estudio de fase 3, aleatorizado, multicéntrico y doble ciego para investigar la eficacia y seguridad de retatrutida una vez por semana en comparación con placebo en participantes adultos con diabetes tipo 2, insuficiencia renal moderada o grave con control glucémico inadecuado con insulina basal con o sin metformina y /o inhibidor de SGLT2 (TRANSCEND-T2D-3)
J1I-MC-GZQA
T2DM & CKD
NN9388-7700
NN9388-7700
Efficacy and safety of cagrilintide s.c. co-managed. 2.4 mg in combination with semaglutide s.c. 2.4 mg (CagriSema s.c. 2.4 mg/2.4 mg) once weekly compared to semaglutide, cagrilinitide, and placebo in people with chronic kidney disease and type 2 diabetes
ZENITH
Phase III, Multicenter, Randomized, Double-Blind Study to Evaluate the Efficacy, Safety and Tolerability of Zibotentan/Dapagliflozin Compared to Dapagliflozin Alone in Participants with Chronic Kidney Disease and High Proteinuria
Completed Studies - Nephrology
ZENITH HP /D4325C00007
Study for the Identification and Characterization of Patients with Chronic Kidney Disease and Proteinuria.
CR845-310302 / KICK 2/CARA
Patients with Advanced Chronic Kidney Disease with Moderate to Severe Pruritus and not on Dialysis
CR845-310302 2048/0010
STABILIZE
To evaluate the effect of sodium zirconium cyclosilicate on the progression of chronic kidney disease (CKD) in participants with CKD and hyperkalemia or at risk of hyperkalemia (STABILIZE-CKD)
BI 1378-0005
Randomized, double-blind, placebo-controlled, twelve parallel group study to investigate the efficacy and safety of multiple doses of oral BI 690517 over 14 weeks, alone and in combination with empagliflozin, in patients with diabetes and non-diabetic chronic kidney disease
6 + 5
FLAIR
Phase 2B, Randomized, Double-Blind, Placebo-Controlled, Multicenter, Multi-Dose Study of AZD5718 in Participants With Chronic Proteinuric Kidney Disease
Zenith
Phase 2b, multicenter, randomized, double-blind, active ingredient-controlled study,
of parallel dose-finding groups to evaluate the efficacy, safety, and
tolerability of zibotentan and dapagliflozin in patients with chronic kidney disease with
estimated glomerular filtration rate (eGFR) >=20 ml/min/1.73 m2”
Pulmonology
Active Studies - Pulmonology
TANGO
Un ensayo de 52 semanas, aleatorizado, doble ciego, multicéntrico, de grupos paralelos de 2 brazos que evalúa la eficacia y seguridad del inhalador de polvo seco (DPI) CHF6001 (dosis diaria total 3200 ug) como complemento al corticosteroide inhalado de dosis media o alta de mantenimiento en combinación con agonistas ß2 de acción prolongada en sujetos con asma no controlada
GB43374 OLE – ALNASA
Phase III multicenter open-label extension (OLE) study to evaluate the long-term safety and efficacy of astegolimab in combination with standard of care (SOC),
DOMINICA
AstraZeneca: D3250C00024
Parexel: 268888
Phase 3 Efficacy and Safety Study of Benralizumab in Pediatric Patients with Severe Eosinophilic Asthma, Time to First Asthma Exacerbation, Multicenter, Randomized, Double-Blind, Parallel Group, Placebo-Controlled
Code
CALM Bellus
A Phase 3, 12-Week, Double-Blind, Placebo-Controlled, Parallel-Arm Efficacy and Safety Study
of BLU-5937 in Adult Participants With Refractory or Unexplained Chronic Cough (RCC)
(CALM-1)
Pillar – CLI-06001AA1-05
A 52-week, placebo- and active-controlled (roflumilast, Daliresp® 500 µg) study to evaluate the efficacy and safety of two doses of CHF6001 DPI (tanimilast) as an adjunct to triple maintenance therapy in subjects with COPD and chronic bronchitis.
TRITON
Double-blind, multinational, multicenter, randomized, placebo-controlled, three-way crossover study to evaluate the effect of a triple combination of beclometasone dipropionate and formoterol fumarate plus glycopyrronium (CHF5993) and a double combination of beclometasone dipropionate plus formoterol fumarate formoterol (CHF 1535) Both administered via pMDI in pulmonary hyperinflation and exercise endurance time in subjects with chronic obstructive pulmonary disease (COPD)
PILASTER
52-Week Placebo-Controlled Study to Evaluate the Efficacy and Safety of 2 Doses of CHF6001 DPI (Tanimilast), as an Adjunct to Triple Maintenance Therapy in Subjects With COPD and Chronic Bronchitis
Completed Studies - Pulmonology
ALIENTO
Phase III multicenter open-label extension (OLE) study to evaluate the long-term safety and efficacy of astegolimab in combination with standard of care (SOC),
ASPEN INS1007-301
The primary objective of this study is to evaluate the effect of brensocatib at doses of 10 mg and 25 mg compared to placebo on the rate of pulmonary exacerbations (PE) during the 52-week treatment period.
MATINE
208657
“Multicenter, randomized, double-blind, parallel-group, placebo-controlled study of mepolizumab 100 mg s.c. as an add-on treatment in participants with COPD with frequent exacerbations and characterized by eosinophil levels (Study 208657)”
Oncology
Active Studies - Oncology
VERBENA
A randomized, double-blind study to compare the pharmacokinetics, between ABP 206 and Nivolumab (Opdivo®) in subjects with stage III or IV melanoma resected in the adjuvant setting.
Completed Studies - Oncology
TROPION 02
Phase 3, Open-Label, Randomized Study of Datopotamab Deruxtecan (Dato-DXd) Versus Investigator's Choice of Chemotherapy in Patients With First-Line Inoperable or Metastatic Locally Recurrent Triple-Negative Breast Cancer Who Are Not Candidates for Inhibitor Therapy PD1/PD-L1 (TROPION Mama02)
lidERA/TRIO045
Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared to Physician's Choice of Adjuvant Endocrine Monotherapy in Participants With Estrogen Receptor-Positive, HER2-Negative Early Breast Cancer (lidERA Breast Cancer)
TROPION 01
No data available at this time
213400
“Phase 3, randomized, double-blind, placebo-controlled study,
multicenter to compare niraparib plus pembrolizumab versus placebo plus
pembrolizumab as maintenance treatment in participants whose disease
remained stable or responded to first-line platinum-based chemotherapy
with pembrolizumab against stage IIIB or non-small cell lung cancer
IV”
AMEERA – 5
Phase 3, randomized, multicenter, double study
amcenestrant cecum (SAR439859) plus palbociclib
compared to letrozole plus palbociclib for
treatment of patients with ER(+) breast cancer,
HER2(–) who have not received treatment
previous systemic antineoplastic for the disease
advanced
CUSA
Phase 3, Randomized, Double Blind, Active
and Placebo Controlled Study on the Use of CUSA-081 for Dysfunctional Central Venous Access
Devices [CVAD]
Rheumatology
Active Studies - Rheumatology
APATURA
DRI17821
Un estudio de fase 2, aleatorizado, doble ciego, controlado con placebo, de rango de dosis, eficacia y seguridad de SAR441566 más metotrexato en adultos con artritis reumatoide de moderada a grave.
1366-0031
Phase II, randomized, placebo-controlled, double-blind, parallel-group, efficacy and safety study of BI 685509 in adults with early progressive diffuse cutaneous systemic sclerosis.
MARS-17
Estudio de fase 2, multicéntrico, aleatorizado, doble ciego, controlado con placebo, de búsqueda de dosis (MARS-17) de GSK3858279 en participantes adultos con dolor moderado a severo ocasionado por artrosis de rodilla.
EMERALD
230LE306
"Un estudio de extensión a largo plazo, multicéntrico, aleatorizado, a ciegas, de fase 3 para evaluar la Seguridad y eficacia de BIIB059 en participantes adultos con lupus eritematoso sistémico (LES) activo"
WILLOW LTE MS200569_0048
A Phase II, Double-Blind, Variable-Dose, Parallel, Long-Term Extension Study to Evaluate the Safety and Efficacy of Enpatoran in Participants With Subacute Cutaneous Lupus Erythematosus, Discoid Lupus Erythematosus, and/or Systemic Lupus Erythematosus Who Have Completed the WILLOW study treatment
(MS200569_0003)
AMETHYST
230LE301, Part A (Phase 2)/ Part B (Phase 3) Randomized, double-blind, placebo
Multicenter controlled study to evaluate the efficacy and safety of BIIB059 in participants with subacute cutaneous lupus erythematosus and/or chronic cutaneous lupus erythematosus with or without Systemic Manifestations and Refractory and/or Intolerant to Antimalarial Therapy
(AMETHYST)
TOPAZ
The primary objective of this study is to demonstrate the efficacy of BIIB059 compared to placebo in participants with active systemic lupus erythematosus (SLE), who are receiving lupus standard of care (SOC) treatment to reduce disease activity.
Completed Studies - Rheumatology
JASMINE 80202135SLE2001
Phase 2, multicenter, randomized, double-blind, placebo-controlled study of nipocalimab in subjects with active systemic lupus erythematosus (SLE).
WILLOW
The purpose of this proof-of-concept (PoC) and dose-finding (DF) basket study is to evaluate the efficacy and safety of M5049 administered orally for 24 weeks in systemic lupus erythematosus (SLE) and cutaneous lupus erythematosus ( CLE; subacute cutaneous lupus). erythematosus [SCLE] and/or discoid lupus erythematosus [DLE]) participants in a randomized, double-blind, placebo-controlled, parallel, adaptive, and dose-ranging setting. Study Duration: 33 weeks Visit Frequency: Every 2 to 4 weeks M5049 is not available through an expanded access program.
CONTRAST X (EXTENSIÓN)
“Estudio multicéntrico, de extensión a largo plazo para evaluar la seguridad y eficacia de GSK3196165 en el tratamiento de artritis reumatoide.”
Our Professionals
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Doctors
Internal Medicine and diabetes
Nutrition
Ophthalmology
Nephrology
Infectology
Dermatology
Pulmonology
Hematology
Rheumatology
Administrative and technical area
Regulatory - Start Up
Executive Area
Infrastructure
Facilities
- 450 square meters
- 10 Offices
- Box for sample extraction
- Box for ECG performance
- Wardrobe for patients
- Pharmacy with security code, alarm and cold chain
- Calibrated thermometers
- Lockable storage location for files and medical records
- Storage space with security code for returned medication.
- Monitoring room
- Breakfast area for patients
- Protected cardio space
Technology
- Fully computerized center
- Protected digital information
- 24 hour fax with direct line
- Printer with scanner on each floor
- Generator set to ensure cold chain in pharmacy
- Wifi
- 24 hour monitoring
Equipment
- Refrigerators and freezers with calibrated thermometers
- Laminar flow hood Blood pressure monitors
- Roma scales
- 2 Centrifuges
- Incubator
- Electrocardiograph
- Spirometer
- Defibrillator
- Cabinet with basket for pathological waste and periodic withdrawals by Environmental Systems
Our Sponsors
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